HealthDay

Robust Evidence Lacking for Many Cardiovascular Guidelines

THURSDAY, March 21, 2019 (Pharmacist's Briefing) -- Only a small proportion of recommendations in major cardiovascular society guidelines are supported by evidence from multiple randomized controlled trials (RCTs) or a single large RCT, according to a study published in the March 19 issue of the Journal of the American Medical Association. This cardiovascular medicine theme issue was released early to coincide with the annual meeting of the American College of Cardiology, held from March 16 to 18 in New Orleans
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Patients With Diabetes at Increased Risk for Sleep Apnea

WEDNESDAY, March 20, 2019 (Pharmacist's Briefing) -- Patients with type 2 diabetes are at increased risk for developing obstructive sleep apnea (OSA), independent of other factors, according to a study published online March 12 in Diabetes Care
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HealthDay

Healthy Food Rx Could Be Cost-Effective for Medicare, Medicaid

WEDNESDAY, March 20, 2019 (Pharmacist's Briefing) -- Economic incentives for healthier foods through Medicare and Medicaid could generate substantial health gains and be highly cost-effective, according to a study published online March 19 in PLOS Medicine
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FDA: First Treatment Approved Specifically for Postpartum Depression

WEDNESDAY, March 20, 2019 (Pharmacist's Briefing) -- Zulresso (brexanolone) injection has been approved for intravenous (IV) use in the treatment of postpartum depression (PPD) in adult women, marking the first drug approved specifically for PPD, the U.S. Food and Drug Administration announced yesterday
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HealthDay

Recommendations Issued for HSCT in Multiple Myeloma

WEDNESDAY, March 20, 2019 (Pharmacist's Briefing) -- A consensus statement for the use of hematopoietic stem cell transplantation (HSCT) in the treatment of multiple myeloma (MM) has been developed by Mayo Clinic physicians; the recommendations were published in the March issue of Bone Marrow Transplantation
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CDC: New HIV Transmission Often From Those Unaware of Infection

TUESDAY, March 19, 2019 (Pharmacist's Briefing) -- Most new HIV transmissions are from people who do not know they have HIV infection or are aware of infection but are not receiving care, according to research published in the March 18 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report
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HealthDay

Light Physical Activity Tied to Lower CHD, CVD Risk in Women

TUESDAY, March 19, 2019 (Pharmacist's Briefing) -- Light physical activity (PA) is associated with reductions in coronary heart disease (CHD) and cardiovascular disease (CVD) among older women, according to a study published online March 15 in JAMA Network Open
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HealthDay

Favorable Outcomes Seen in Long Term for ALLR3 Trial

TUESDAY, March 19, 2019 (Pharmacist's Briefing) -- For children with B-cell precursor acute lymphoblastic leukemia with late bone marrow relapse, risk stratification by minimal residual disease seems to be an effective strategy for treatment, according to a study recently published in The Lancet Haematology
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HealthDay

In Utero Ultrafine Particle Exposure Tied to Asthma in Offspring

MONDAY, March 18, 2019 (Pharmacist's Briefing) -- Exposure to ultrafine particles (UFPs; <0.1 μm) during the second trimester in utero is linked to the subsequent onset of asthma in children, according to a study published online Feb. 20 in the American Journal of Respiratory and Critical Care Medicine
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HealthDay

Active Interventions Generally Helpful for Urinary Incontinence

MONDAY, March 18, 2019 (Pharmacist's Briefing) -- Most active interventions are more likely than no treatment to improve outcomes for women with either stress or urgency urinary incontinence (UI), according to a review published online March 19 in the Annals of Internal Medicine
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HealthDay

Influences on New NIH Policy for Age Limits in Research Explored

FRIDAY, March 15, 2019 (Pharmacist's Briefing) -- Authors of a paper recently published in the Journal of the American Geriatrics Society describe factors that influenced the new National Institute of Health policy that requires funded scholars to eliminate arbitrary age limits in their work
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HealthDay

Testosterone Therapy in Hypogonadism Can Prevent Progression to T2DM

FRIDAY, March 15, 2019 (Pharmacist's Briefing) -- Testosterone therapy (TTh) can prevent progression to type 2 diabetes (T2D) in men with prediabetes and hypogonadism, according to a study published online March 12 in Diabetes Care
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HealthDay

CDC: 2000 to 2017 Saw Increase in Mortality Due to Dementia

THURSDAY, March 14, 2019 (Pharmacist's Briefing) -- Mortality attributed to dementia increased from 2000 to 2017, with variation by age, race, and sex, according to a study published online March 14 in National Vital Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention
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HealthDay

Having Affected Relatives Linked to Increased Alzheimer Risk

THURSDAY, March 14, 2019 (Pharmacist's Briefing) -- Having affected first-degree, second-degree, or third-degree relatives (FDRs, SDRs, and TDRs) is associated with an increased risk for Alzheimer disease (AD), according to a study published online March 13 in Neurology
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HealthDay

Troponin Assay Confusion May Cause Misdiagnosis of Acute MI

THURSDAY, March 14, 2019 (Pharmacist's Briefing) -- The 99th centile of high-sensitivity cardiac troponin I (hs-cTnI) concentration is substantially higher in a hospital population than the manufacturer's recommended upper limit of normal (ULN), according to a study published online March 13 in The BMJ
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HealthDay

Nasal Spray Vaccine Against Flu Acceptable in 2019 to 2020

THURSDAY, March 14, 2019 (Pharmacist's Briefing) -- The American Academy of Pediatrics (AAP) plans to advise families to vaccinate children against influenza with either the flu shot or nasal spray vaccine during the 2019 to 2020 flu season, in contrast to the academy's preference for the injected vaccine over the nasal spray during the previous two flu seasons, the AAP announced today
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HealthDay

Resistance Training May Prevent Type 2 Diabetes Progression

WEDNESDAY, March 13, 2019 (Pharmacist's Briefing) -- Resistance training (RT) may be a viable option for patients with prediabetes seeking to prevent or delay progression to type 2 diabetes (T2D), according to a study published online Feb. 15 in Diabetes/Metabolism Research and Reviews
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HealthDay

FDA Approves New Generic Valsartan to Ease Shortage

WEDNESDAY, March 13, 2019 (HealthDay News) -- The U.S. Food and Drug Administration on Tuesday approved a new generic version of the high blood pressure/heart failure drug valsartan, saying the move might help ease the current medication shortage
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HealthDay

Tramadol May Up Mortality Risk in Osteoarthritis Patients

TUESDAY, March 12, 2019 (Pharmacist's Briefing) -- The initial prescription of tramadol compared with commonly prescribed nonsteroidal anti-inflammatory drugs may be associated with increased all-cause mortality among patients with osteoarthritis, according to a study published in the March 12 issue of the Journal of the American Medical Association
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HealthDay

CDC: Flu Season May Have Peaked

MONDAY, March 11, 2019 (Pharmacist's Briefing) -- It looks like the flu season has peaked in the United States, though there has been a recent rise in the number of cases involving a more severe flu strain
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HealthDay

Dual Receipt of Opioids Tied to Increased Risk for OD Death

MONDAY, March 11, 2019 (Pharmacist's Briefing) -- For veterans enrolled in the U.S. Department of Veterans Affairs (VA) and Medicare Part D, receipt of opioids from both VA and Part D is associated with an increased likelihood of death from prescription opioid overdose, according to a study published online March 12 in the Annals of Internal Medicine
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HealthDay

Long-Acting Regimen Noninferior to Daily ART for HIV-1

MONDAY, March 11, 2019 (Pharmacist's Briefing) -- Monthly long-acting (LA) cabotegravir (CAB) and rilpivirine (RPV) are noninferior to daily regimens for patients with HIV-1, according to two studies presented at the Conference on Retroviruses and Opportunistic Infections, held from March 4 to 7 in Seattle
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HealthDay

Raspberries May Aid Glucose Control With Prediabetes

THURSDAY, March 7, 2019 (Pharmacist's Briefing) -- Eating red raspberries may help with glucose control in people with prediabetes, according to a small study published online Feb. 14 in Obesity
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HealthDay

High-Quality, Plant-Based Diet Tied to Lower Risk for CVD Mortality

THURSDAY, March 7, 2019 (Pharmacist's Briefing) -- Increasing consumption of high-quality, plant-based foods decreases the risk for death from cardiovascular disease (CVD), according to a study presented at the American Heart Association Epidemiology and Prevention/Lifestyle and Cardiometabolic Health 2019 Scientific Sessions, held from March 5 to 8 in Houston
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HealthDay

AAN: Sweetened Drinks Linked to More Severe Disability in MS

WEDNESDAY, March 6, 2019 (Pharmacist's Briefing) -- Sugar-sweetened beverage consumption is associated with an increased risk for severe versus mild-to-moderate disability among individuals with multiple sclerosis (MS), according to a study scheduled for presentation at the upcoming annual meeting of the American Academy of Neurology, to be held from May 4 to 10 in Philadelphia
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HealthDay

Behavioral Intervention Ups Physical Activity in T2DM

WEDNESDAY, March 6, 2019 (Pharmacist's Briefing) -- A behavioral intervention results in a sustained increase in physical activity and decrease in sedentary time among patients with type 2 diabetes, according to a study published in the March 5 issue of the Journal of the American Medical Association
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HealthDay

Studies Look at Ways to Reduce Depressive Episodes in Obese

TUESDAY, March 5, 2019 (Pharmacist's Briefing) -- For overweight adults with depression, daily multinutrient supplements and individual or group therapy sessions do not reduce major depressive disorder (MDD) episodes over one year, but an integrated intervention appears to be beneficial, according to two studies published in the March 5 issue of the Journal of the American Medical Association
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HealthDay

AASM Releases New Sleep Apnea Treatment Guideline

TUESDAY, March 5, 2019 (Pharmacist's Briefing) -- A new guideline, published Feb. 15 in the Journal of Clinical Sleep Medicine, establishes clinical practice recommendations for positive airway pressure (PAP) treatment of obstructive sleep apnea (OSA) in adults
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HealthDay

Children With Atopic Dermatitis Have Worse Sleep Quality

TUESDAY, March 5, 2019 (Pharmacist's Briefing) -- Children with atopic dermatitis (AD) have worse sleep quality, according to a study published online March 4 in JAMA Pediatrics
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Higher Intake of Whole Grains May Lower Risk for Liver Cancer

MONDAY, March 4, 2019 (HealthDay News) -- Higher intake of whole grains may be associated with a lower risk for hepatocellular carcinoma (HCC) among U.S. adults, according to a study published online Feb. 21 in JAMA Oncology
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